New evidence confirms COVID-19 vaccines are overwhelmingly safe::More than 38 million COVID-19 vaccine doses have been administered in Ontario as of Oct. 8, with 23,002 reports of adverse reactions, an incidence of 0.06 per cent, Public Health Ontario says

  • @k110111@feddit.de
    link
    fedilink
    English
    531 year ago

    Guys the reason this study is important is because covid vaccines used revolutionary technology, they were the first to use mRNA based protein. If you remember we sequenced its genome within 40 days the making the vaccine was considerably easy. This is the main reason it took only 2 years for the vaccine to be made compared to years of development for other vaccines.

    • Match!!
      link
      fedilink
      English
      231 year ago

      It also means that, with this new vaccine technology, we can develop vaccines faster and faster

        • nickwitha_k (he/him)
          link
          fedilink
          English
          91 year ago

          Pretty sure that mRNA printers are indeed a thing. But, you’ll probably have better efficiency if you only use it for the template and use RNA-copying enzymes for the bulk of the work.

            • nickwitha_k (he/him)
              link
              fedilink
              English
              31 year ago

              I studied this stuff back in uni, is really fascinating, though, I’m more familiar with DNA amplification via Polymerase Chain Reaction (PCR).

              If you’re interested, I’ll give some details here and a link to a neat video. Effectively, there is an enzyme in our cells called DNA Polymerase. It literally scans a strand of DNA and copies it. In PCR, they use a solution of nucleotides (building blocks of DNA) and the DNA Polymerase extracted from a heat-loving microbe. The DNA to be copied (amplified) is added, and then the temperature maintained at the enzyme’s optimal temperature (higher than usual for other organisms). The solution is allowed to “stew” for a set amount of time, then, filtered to separate the DNA (lots of copies of the original) from everything else.

              A similar process can be done using an RNA polymerase (possibly modified) in order to amplify mRNA. So, once the template is printed, it gets put in the solution and RNA polymerases go brrrrrr.

              https://youtu.be/wJyUtbn0O5Y?si=Gkz8B87iY-35GvuZ

  • @Jackthelad@lemmy.world
    link
    fedilink
    English
    -311 year ago

    The thing that increased anti-vaxx sentiment and theories of the vaccines killing you or whatever, was governments around the world going full fash with them.

    If you don’t take the vaccine, you can’t enter establishments, you can’t work, you’ll be denied healthcare ahead of someone who has been vaccinated, fined if you don’t take it (in the case of Germany) etc etc. If you want people to get vaccinated en masse, this is entirely the opposite way of doing it. It’s no surprise that there’s now been a decline in vaccine uptake in general.

    That whole period when the vaccines first came out and the governmental coercion has actively damaged public health messaging for the foreseeable future.

    • hh93
      link
      fedilink
      English
      241 year ago

      The whole period before about behaving responsibility and using masks showed you all you needed to know about how responsible and interested in the general wellbeing most people were so it only made sense to not leave it up to chance with that.

      And it’s not like anyone was forced - only other people were secured from coming in contact with irresponsible and self-centred people that couldn’t care less about them

      • @Jackthelad@lemmy.world
        link
        fedilink
        English
        -171 year ago

        Here in the UK, during the first lockdown, social distancing and the like was adhered to do quite well. More so than the scientists and government expected. Mainly because it was simple instruction that didn’t stop you from going about your business when you needed to get your groceries.

        And it’s not like anyone was forced

        No, they were just told they couldn’t participate in society. But then when they realised that the messaging wasn’t working, they gave up on it.

    • @kescusay@lemmy.world
      link
      fedilink
      English
      271 year ago

      full fash

      You mean, they told people they couldn’t spread a dangerous virus to others? How very “fash.”

      Fuck that bullshit.

        • @kandoh@reddthat.com
          link
          fedilink
          English
          201 year ago

          People die in car accidents despite wearing their seatbelts. Forcing people to wear their seatbelts while driving is wrong because it doesn’t grant 100% survival rate.

          👍

  • @AAA@feddit.de
    link
    fedilink
    English
    71 year ago

    I didn’t need a study for that. I mean we vaccinated ones are still pretty much alive, despite all the warnings of the dum-dums.

  • @doingthestuff@lemmy.world
    link
    fedilink
    English
    -14
    edit-2
    1 year ago

    Great! Can we see the 10/20/50 year data?

    I’m vaccinated, but don’t pretend we don’t find out problems decades later all the time. This headline is stupid.

  • @WallEx@feddit.de
    link
    fedilink
    English
    -191 year ago

    Those are the official numbers, but I’ve heard time and time again from people with vaccine damages, that they have to basically force their doctors to even report their symptoms, so I have my doubts how accurate it is.

      • @WallEx@feddit.de
        link
        fedilink
        English
        11 year ago

        Okay, that’s a nice way to acknowledge legitimate concerns. Or do you have the definitive information, that this doesn’t happen? I know it’s anecdotal, but still

  • Iceblade
    link
    fedilink
    English
    20
    edit-2
    1 year ago

    Anyone know where I can access the report mentioned? It doesn’t seem to be linked anywhere in the article, nor cited by a searchable name…

    Nvm, found it on the website for Public Health Ontario

  • IninewCrow
    link
    fedilink
    English
    6
    edit-2
    1 year ago

    What about their effectiveness?

    I get that the first few versions might have stemmed the tide of the pandemic early on … but how effective are the new doses now?

    I’m not an antivacer but I do question the way the pandemic was handled and continues to be handled. I trust scientists, I trust the medical community, I trust our current level of knowledge and expertise … I even trust our government to do the best they can with what they have … I just don’t trust seeing big corporate interests quietly influencing everything in the background.

    I certainly don’t trust anyone or anything that reprimands me or is threatened by my questions or concerns.

    I would feel a whole lot better about all this if corporate and financial interests were completely disconnected from all our health care and pharmaceutical systems. Basically, anything that has to do with human bodily health should not be controlled or deeply influenced by monied interests.

    • @DoomBot5@lemmy.world
      link
      fedilink
      English
      111 year ago

      It’s as effective as the flu vaccine. Get the version that addresses the latest varients, as previous ones may not be as effective against it.

      • @JonEFive@midwest.social
        link
        fedilink
        English
        51 year ago

        Exactly. Some people get a flu shot every year. Now it’s going to be a flu shot and a covid shot.

        Virus evolves, scientists do their best to predict which particular variants are or will become most prevalent. Vaccinations are made and administered based on that data. Rinse and repeat.

        There are times when the models are wrong or variants progress in unexpected ways. In those cases you might see a mid-year booster.

        Vaccines don’t guarantee you won’t get sick, but they reduce the severity and time to recover if you do get sick with one of the relevant variants. They may even prevent the occurrence of most symptoms depending on the person. .

      • @kobra@lemm.ee
        link
        fedilink
        English
        2
        edit-2
        1 year ago

        What if that 5% resist came with a temporary 36 hour debuff that made your character unplayable?

        Edit: Lmao at people downvoting what they think is an opinion? I’m just adding context that a lot of people do go through pretty severe symptoms. But sure, keep ignoring/downplaying them and complaining about low vaccination rates 😆

        • @JonEFive@midwest.social
          link
          fedilink
          English
          10
          edit-2
          1 year ago

          Show me data indicating that a significant number of people who receive the vaccine are affected to that extent.

          Anecdotally, nobody I know - including myself after being vaccinated multiple times - has had any significant negative reaction unless you count your arm being sore. “Unplayable” is extreme.

          Edit:Wild - thanks everyone for your input. This just says something about basing a knowledge on a limited sample size. I see that it really depends on the person now.

          I personally received the Pfizer shot as did just about everyone I know.

          • @UID_Zero@infosec.pub
            link
            fedilink
            English
            11 year ago

            I’ve had 5 shots of Moderna now, most recently last week. The first one made me feel miserable for a day. I was having chills, and my entire body was sore. I took several naps that day. The others made me sore and a little tired for a day.

            All told, not the worst side effects, but certainly more than a sore arm. And still entirely worth the mild inconvenience.

            I would call my first reaction nearly “unplayable.” I was having issues working (remotely even, a desk job), and I just wanted to sleep most of the day. But people react differently. Sounds like you had no issues, so good for you.

          • @time_lord@lemmy.world
            link
            fedilink
            English
            31 year ago

            My work gave everyone who got it two days off to recover. It’s more like a 20% chance of a 24-48 hour debuff, but you can’t seriously tell me that you haven’t heard of anyone having side effects.

          • @toasteecup@lemmy.world
            link
            fedilink
            English
            2
            edit-2
            1 year ago

            My pre-wife was down for the count for 48-36 hours after getting a vaccine shot. The second round was a little better but not by much.

            I understand I’m just some random person on the Internet but I’m giving factual information in interest of continuing the discussion.

            The interesting thing is that while I was fine after the shots, I was not fine being sick with covid (post shot). I was on bed rest for about 5 days and all I could do was wake up, take aspirin and Tylenol, take a shower because covered in cold sweats, drink lemon ginger tea with honey to soothe the throat, watch 30ish minutes of YouTube and knock myself out with melatonin to repeat the cycle.

            She, on the other hand, was fine getting covid post shot.

            • @JonEFive@midwest.social
              link
              fedilink
              English
              21 year ago

              Yeah, I got COVID after being vaxed too. My biggest symptom was just complete exhaustion and body aches. Mild cough for a couple days. It lasted about 5 days for me too. That said, I wonder how much worse it would have been if I wasn’t vaccinated.

              • @toasteecup@lemmy.world
                link
                fedilink
                English
                11 year ago

                I can’t say I wondered how much worse it would have been without a shot but that’s because it was super bad for me with one ha.

          • ∟⊔⊤∦∣≶
            link
            fedilink
            English
            2
            edit-2
            1 year ago

            Reading all these people’s reactions makes me think I got the placebo. It did nothing to me. It was the pfizer edition, if that makes any difference.

          • @Catoblepas@lemmy.blahaj.zone
            link
            fedilink
            English
            51 year ago

            The COVID boosters make me feel moderately sick and my arm very sore for 2-3 days, in a way most other vaccines don’t. The one time I had COVID I felt like I was one bad day away from winding up in the hospital for weeks, so I’ll take the vaccine every single time I can. If anything I think I feel so bad after the vaccine because COVID itself fucks me up so bad.

          • @tony@lemmy.hoyle.me.uk
            link
            fedilink
            English
            71 year ago

            My first and third vaccine knocked me out for 2 days at a time… unable to even get out of bed.

            Second one, after I’d booked time off work deliberately so I wouldn’t surprise anyone by not being there, I had no issues at all…

          • @Metz@lemmy.world
            link
            fedilink
            English
            21 year ago

            my second and third knocked me out for 3 full days. I was no longer able to get out of bed. I had severe chills and extreme nausea. I practically puked my guts out for 3 days. i know multiple other people that had very similar reactions.

          • @uberkalden@lemmy.world
            link
            fedilink
            English
            21 year ago

            Every shot after the first has knocked me on my ass for 24 hours minimum. Pro vax here. This is a real thing

          • rigatti
            link
            fedilink
            English
            21 year ago

            My first shot, Moderna, knocked me out for about 36 hours. I could only muster up enough energy to get out of bed for a few minutes to eat a bit of cereal and drink some Gatorade. So there’s an anecdote from someone you don’t know.

            That being said, I’d still take that for the 5% resistance boost.

        • @tabular@lemmy.world
          link
          fedilink
          English
          3
          edit-2
          1 year ago

          On hardcore mode with permanent death the chance of a short term de-buff for a long term buff is worth it.

          Pick the right time so you don’t miss out on any one-time events if you’re unlucky.

    • NaibofTabr
      link
      fedilink
      English
      331 year ago

      Their efficacy has been heavily studied and proven.

      versions might have stemmed the tide of the pandemic

      This is straight-up weasel language. There is no (rational) question as to whether the vaccines reduced hospitalizations due to COVID-19, or contraction of COVID-19 in general.

      corporate and financial interests were completely disconnected from all our health care and pharmaceutical systems

      This is not realistic in the slightest. Reasearch requires resources and the time and effort of highly qualified people.

      • @SmoothIsFast@citizensgaming.com
        link
        fedilink
        English
        11 year ago

        corporate and financial interests were completely disconnected from all our health care and pharmaceutical systems

        This is not realistic in the slightest. Reasearch requires resources and the time and effort of highly qualified people.

        It’s extremely realistic, humanity makes the most progress when research does not need to create a monetary benefit. It allows us to explore ideas unabated. While these systems need funding we could take a 1% from military spending and invest with government resources. Hence why the mrna vaccines actually progressed so quickly, they were already being researched by the army for quick and rapid treatment of diseases during combat, i.e. just to solve the problem not just to profit from the tech, they lent that research out and gave grants to the corporations who developed and manufactured the covid vaccines. Internet, developed for combat communications not for profit. Most computer innovations came out of the space race, research without a profit motive. The ideas funded by corporate interests revolve around optimizing profit, not progress, which is why we get planned obsolescence, lack of rights to repair, massive healthcare costs needing insurance offsets, etc. I guarantee you can’t name an actual positive innovation that was spurred purely for profit and not bastardized in the name of profit from a century old idea people forgot about so the company could attribute genius to its wealthy founders crud copy and paste job.

      • IninewCrow
        link
        fedilink
        English
        -31 year ago

        I can agree and accept most debates about this and I probably agree with most of what you present. And I am vaxxed with six COVID vaccines at this point and chances are I’ll continue taking them with a lot of skepticism.

        The biggest issue I have is corporate control.

        I agree that research and development requires money … but that can be achieved through public funds and government programs. What do think is cheaper? Privately owned research that has to be paid for at a premium … or publically developed research that is made open and accessible for other researchers across the globe (who can then collaborate with each other instead of compete behind closed source patents and information)

        I trust the scientists and researchers that develop these medical break throughs … I just don’t trust the private CEOs that hire them or the corporations they work for.

      • Cyborganism
        link
        fedilink
        English
        51 year ago

        You don’t need to be so agressive.

        OP didn’t say that the vaccine didn’t work at first. It’s just that now development has a hard time to keep up with new mutations.

        Also, we don’t need multi billion dollar medical corporations to study and create vaccines. This could be done entirely through a government agency or ministry.

        I agree with OP about how much we should trust corporations. Their bottom line is to make a profit and they’ll do whatever they can to get there. They cut corners and hide facts to avoid losses.

        One such fact that was denied and for which you could get ridiculed was that a certain percentage of the population that received the COVID vaccine had symptoms afterwards that never went away. Like constant headaches and swelling of the brain. Now they explain these to you before you take new doses so that you know the risks. They’re small, but they can happen.

        In fact, ever since my last dose in August I’ve had constant headaches myself and I always feel hungover. It’s permanent. There’s nothing anyone can do about it. At this point I wonder if I should have taken it at all considering the I’ve had so the previous shots before. I only took it because I was traveling for a couple weeks and wanted to increase my chances of not getting sick.

  • @JdW@lemmy.world
    link
    fedilink
    English
    441 year ago

    We always knew/suspected this. But the ones that do the fearmongering around vaccines will not be interested in facts…

    • r3df0x ✡️✝☪️A
      link
      fedilink
      English
      31 year ago

      Not just that, but a lot of them see it as resistance to authority, even if they don’t think there’s a serious risk. This is inevitably what happens when things get forced and mandates get imposed. It naturally causes people to push back against it.

      • BreakDecks
        link
        fedilink
        English
        31
        edit-2
        1 year ago

        No, this is what happens in a rigidly individualistic western countries like the USA, UK, and Australia where people act like children screaming “you can’t tell me what to do!”, even when it’s just the health department asking you to stay safe.

        There were no forced vaccine mandates in the USA, so I don’t really know what you’re talking about when you say that this was inevitable. Right-wingers just pretended that there was a mandate so that they could do performative resistance, but you might have noticed, there was no government-imposed punishment for refusing, just the natural consequence of drowning in your own sputum in the ICU.

        • r3df0x ✡️✝☪️A
          link
          fedilink
          English
          -301 year ago

          Various employers imposed mandates, so there were mandates.

          When neo-fascists try to impose things, that naturally creates resentment. All the people calling for mandates are the reason the reason why there was resistance.

          • BreakDecks
            link
            fedilink
            English
            141 year ago

            “Fascism is when employers tell their employees what to do.”

          • @EatATaco@lemm.ee
            link
            fedilink
            English
            101 year ago

            You’ve got yourself very turned around: the only reason there were talk of mandates is because we knew that, without them, people wouldn’t get the vaccine. Fear of vaccines long predates any mandates. It basically started the minute the first vaccine was developed.

            I’m not saying no one refused it because of talk of mandates, but the overall trend would be that without a strong incentive, some people would not get it, whether it just because of laziness, procrastination, or simply being on the fence about it.

            • r3df0x ✡️✝☪️A
              link
              fedilink
              English
              -201 year ago

              Not if there are multiple people in the car. As soon as there’s another person in the car, it’s not victimless.

              • @emergencyfood@sh.itjust.works
                link
                fedilink
                English
                31 year ago

                Vaccines work when everyone uses them. There are a small number of people who cannot be vaccinated due to medical reasons. They rely on others being vaccinated. So when a lot of people who can take the vaccine refuse to do so, they put these people in danger.

      • @EatATaco@lemm.ee
        link
        fedilink
        English
        31 year ago

        Yeah, so much of it is just contrarianism. These people think that if they blindly reject everything that comes from an official source that they are substantially different than the people who blindly accept everything that comes from an official source.

        • r3df0x ✡️✝☪️A
          link
          fedilink
          English
          -151 year ago

          Experts have lied repeatedly and trust in them is at an all time low. If it wasn’t for the talk of mandates, more people would have got the vaccine. Pushback is a natural consequence of trying to force things.

          • @EatATaco@lemm.ee
            link
            fedilink
            English
            141 year ago

            Experts have lied repeatedly

            A completely vague statement - which is almost certainly untrue or a gross misrepresentation of reality - that basically justifies believing whatever you want. I’ve seen this plenty throughout my life, but it’s become especially popular since the start of the pandemic.

  • Ted Jackson
    link
    fedilink
    English
    -131 year ago

    Something, something, comorbidities…

    Sorry, I forgot that only applies to COVID deaths.

    • Ted Jackson
      link
      fedilink
      English
      11 year ago

      Obviously people misunderstood. I’m very much pro vaccine - fully vaccinated and triple boosted.

      I was making reference to the fact that anti-vaxxers were citing comorbidities in regards to COVID deaths to downplay the numbers while refusing to do so for deaths shortly after vaccination. This was especially galling in light of the fact that the first groups vaccinated were the most vulnerable: the elderly.

  • @madcaesar@lemmy.world
    link
    fedilink
    English
    121 year ago

    I’m fully pro vaccine and I’m happy for these studies. Nothing wrong about getting more data and confirming or revisiting things based on said results.

    Science is not afraid of being double checked.

    • @SuckMyWang@lemmy.world
      link
      fedilink
      English
      7
      edit-2
      1 year ago

      They’re not safe. They’re 0.06% harmful. That number is probably a lie too, in reality with all the cover ups and bad incentives the number could be as high as 0.1% harmful, that means 40% of cases were covered up or hidden by nurses and doctors who actively went against their hippocratic oath and did something malicious and counter effective to their job. And they don’t even clearly define what harmful is. How many of those 0.1% had mild head aches or nausea? Everyone is stupid but me.

      /s

      But in all seriousness I’m not sure if it’s better to admit that it’s not 100% safe because a lot of people think they will be the unlucky one out of 1000 to get a headache or a mild rash or the 1 out of 100000 that has something more severe. People who are generally anti vax have a hard time grasping these numbers and also seem to be completely wilfully blind to the increased danger from getting actual Covid. They think they’ll be fine and either won’t get it or it won’t be bad yet at the same time think they’ll be the unlucky one to get sick from the vaccine

      • @NocturnalMorning@lemmy.world
        link
        fedilink
        English
        8
        edit-2
        1 year ago

        I usually tell people that it’s safer than birth control. 1 in 1000 women experience severe complications from birth control, and we hand that stuff out like candy.

          • @NocturnalMorning@lemmy.world
            link
            fedilink
            English
            11 year ago

            Depends on if people are willing to listen to facts of incidence of actual adverse effects from the vaccine or not, something like 1 in 2.6 million people will see adverse side effects (depending on source of statistic). Also depends on what health issue you’re looking for issues with. But the overwhelming concensus is that the vaccine is safe. 1 in 1000 is orders of magnitude larger than the covid vaccine adverse effects.

  • @kandoh@reddthat.com
    link
    fedilink
    English
    921 year ago

    There was a 50/50 split in the US Senate when the vaccine came out. Every member of that group was vaccinated. They were the first members of the population to be vaccinated. If any of the ancient senators had died, the balance of power would have shifted in a huge way.